Complications after a heart attack (myocardial infarction) | NCLEX-RN | Khan Academy

Complications after a heart attack (myocardial infarction) | NCLEX-RN | Khan Academy


– [Voiceover] After you’ve
had a myocardial infarct, a heart attack, you are prone
to developing complications. A complication in this sort of context is essentially another
disease or condition that crops up as a result
of your myocardial infarct. Most complications tend to occur within the first few weeks
after having a heart attack, so let’s look at some of
the major complications that can occur after myocardial infarct, and let’s sort of do this
in a step wise fashion to make everything sort of
flow logically in our heads. We can say that myocardial infarcts cause three major problems
with our hearts, right? So, one of the things
is they cause our heart to have decreased contractility, because after a heart attack,
you’ve sustained some damage to your heart muscle, so it
can’t always contract very well. You also get this electrical
instability in your heart because all of the ions that
sort of move back and forth across your heart muscle cell membranes to maintain your electrical
gradients, or your heartbeats, properly, they all get really disrupted so you have this electrical instability. You also get tissue necrosis, right? You get death of some of
your heart muscle cells. These three sort of effects of
having a myocardial infarct, they really underly all of
the downstream complications that are possibly going to crop up. So how does reduced contractility do that? Well, if your heart’s
not contracting properly, then you’re not going
to effectively be able to push blood out of your left ventricle to the rest of your body, right? So you end up in a
state called hypotension and hypotension just means that you have pathologically low blood pressure. When you have pathologically
low blood pressure, you’re not going to be able
to fill your coronary arteries with enough blood, all
the blood that they need. Remember, besides the coronary artery that’s been blocked to result
in your myocardial infarct, there are still other coronary
vessels that needs to have a healthy supply of blood coming to them so that they can in turn supply blood to the rest of your heart muscle, right? The heart muscle that isn’t infarcted. So if they’re not getting enough blood, then you’ll start to get
ischemia in the muscle and other parts of your heart. If you get ischemia in
other parts of your heart, then that will cause more of
your heart muscle all over to not contract properly and eventually, you might not be able to maintain your cardiac output at all and end up in a condition
called cardiogenic shock and because this wall
here, and we’re assuming that it’s this wall that’s been sort of injured in the heart attack, because this wall isn’t
contracting very well, you’d be predisposed to
forming a thrombus, a clot, on the inside of that
left ventricle there, because when blood isn’t
constantly moved around as it might not be in
that little area there, it tends to clot and why is that bad? Well, sometimes they
can kind of flick off, become separated off of the
left ventricle wall there and travel through the aorta and into other vessels of the body where they might get stuck and cause an infarction in
another part of the body. For example, if one
went up into your brain, it might get stuck in one
of your cerebral vessels and cause a stroke, so embolism
is a potential problem. Embolism is the mobilization
of a thrombus, a clot. Alright, what about this
electrical instability over here? Well, the electrical instability
can cause arrhythmias, which is when your heart
doesn’t beat with a normal, regular rhythm like it’s supposed to. Again, that’s due to a
combination of things. That’s due to sort of
disorganized ion movement within the cardiomyocytes,
and it could also be due to a disrupted electrical conduction
system within the heart. I should mention, as part of this conduction system compromization here the two major pace maker
centers in your heart are located in your right atrium, so you’ve got your
sinoatrial node about there and you have your
atrioventricular node around here and these two nodes are really responsible for regulating the normal
rhythm of your heart and so if you happen to
have a myocardial infarct that affected the right atrium,
where both these nodes live, you would probably end
up developing an arythmia because you’d potentially knock out the two biggest regulators
of your heart beat, your heart rate and rhythm. Alright, what about this
tissue necrosis thing? Well, remember, necrosis just
refers to death of something so in this case, death
of the heart tissue. Well, remember after a myocardial infarct, you get a whole bunch of immune cells that come into your heart and
try to sort of tidy things up after your heart attack, and when you’re immune cells are involved with sort of tidying something up, that’s called an inflammatory reaction, and you might start to
get this inflammation around the outside of your heart. I’m drawing this
inflammation in a pink here. Pink is supposed to represent
all those white blood cells as part of your immune system, mediating this inflammatory response here on the outside of your heart. Now, remember your heart sort of sits inside this fibrous sack. It’s encased by this fibrous sort of cover called your pericardium. Your pericardium, peri meaning around and cardium referring to your heart. When you get all this
inflammatory sort of stuff happening on just beneath the pericardium on the outside of the heart, you could irritate your pericardium and you could end up with a condition called pericarditis. Now, that’s not all that
tissue necrosis can do. It can do some pretty nasty stuff here. So, let’s say that you
start to get necrosis of your septum here,
there wall that separates your left ventricle and
your right ventricle. Well, you could probably imagine that that wouldn’t be very good at all. Your oxygenated blood in
your left side of your heart and your deoxygenated blood in
your right side of your heart they would mix, and you
would probably end up with a pretty significant hypoxemia, or low oxygen level in your blood. A ventricular septal defect
would also cause some damage to the arteries in your lungs, because if you can imagine, blood from this high pressure system on the left side of your heart would sort of cross through this defect over to the right side of your heart and be pushed up through to
your pulmonary circulation. That’s not good for your
pulmonary circulation. It can actually cause some
pretty big damage there. What else will tissue necrosis do? Well, what if you get that
necrosis over on this side? Or, really, any other muscle that forms the outer wall of the heart? Well, where do you think
blood in the heart would go if all of a sudden there
was no wall anymore? It would just burst out of the heart. So, tissue necrosis can also cause a rupture of the ventricle. But remember this
pericardium we talked about? This really tough, fibrous
sack that encases the heart? The blood would then just get
trapped inside the pericardium and it would start to sort of
build up in the pericardium and track along the outer heart muscle and the inside the pericardium so that, obviously, would
put a stress on the heart and prevent it from beating as well, and you’d end up with a complication called cardiac tamponade. Tissue necrosis is not done yet though. One of the more common issues that happens as a result of tissue
necrosis is this here. You’ve got these muscles in
the bottoms of your ventricles called your papillary muscles and what your papillary muscles do is they sort of hold on to
the cusps of your valves, the flaps of your valves,
using these structures called chordae tendineae. They’re these sort of tough,
durable, string-like things. So the papillary muscles
and the chordae tendineae work together to make sure
that during a heart beat, when your ventricles contract, your mitral valve and your tricuspid valve over on the right side, you
have a set of papillary muscles and chordae tendineae over there as well, they make sure that the
cusps of your valves don’t invert up into the atria, and so sometimes after a heart attack, one or more of these papillary
muscles will become necrosed, it will die off. When it dies off, all of a sudden now, the valve flap that it was
holding on to can invert. It can go up into the left atrium. This means that when
the ventricle contracts to push blood out into the
aorta, to get around the body, blood can now get back
up into the left atrium. This is called having a leaky valve or a regurgitant valve. In this case, since it’s the mitral valve, we call this mitral regurgitation. So, just before we finish up, let me just draw your attention to this. If your heart has decreased contractility then it’s going to have to work harder to maintain proper profusion
of your body with blood. If you have a mitral regurgitation, then again, your heart’s going
to have to work a lot harder to maintain proper profusion
of your body with blood. If you have a ventricular
septal defect, again, your heart is going to have
to start working a lot harder. So these three conditions in particular, if you develop any of these
after a heart attack or not, you run the risk of developing
congestive heart failure, which is when your heart just
can’t pump out enough blood to meet the oxygen needs of your body.